I don't know about you but I find it annoying when I'm closing out of Photoshop and have several windows/tabs open that I need to answer the question "Save changes before closing?" time after time.
If there is nothing that I need to save here is a quick trick to save you from clicking "No" for all open images.
The next time you have numerous tabs open and are sure you don't have anything you need to save do this.
Select File > Close All. Select the box that says "Apply to All" then click "Don't Save". This of course works for saving all images too.
But be VERY CAREFUL that there are no open images that you really do want to save.